Protein Modification Reagents
Medchemexpress LLC Benzoic acid, 2-[[(18S,21S,22R)-22-amino-21-hydroxy-18-(2-methylpropyl)-... | 1351169-27-1 | 97.9% | 917.14 g/mol | C51H72N4O11 | 5 MG
PROTAC RAR Degrader-1 is a proteolysis-targeting chimera designed to induce degradation of retinoic acid receptor family members by recruiting IAP E3 ligases. It is supplied as a solid research compound characterized by formula C51H72N4O11 and a molecular weight of 917.14 g/mol, intended for cellular studies of RAR/RXR biology.
- Induces degradation of retinoic acid receptors.
- Targets cIAP1 and RXRα.
- Molecular formula C51H72N4O11; molecular weight 917.14 g/mol.
- Purity 97.9%.
- Appearance: solid.
- Solubility: DMSO ≥ 80 mg/mL (87.23 mM).
- Storage: -20°C under nitrogen; in solution store at -80°C up to 6 months or -20°C up to 1 month.
Research Products International Corp Guanidine Hydrochloride, 500 Grams
Protein denaturant used for purifying proteins and nucleic acids.
Medchemexpress LLC BTK degrader-1 | 2377645-56-0 | 99.4% | 925.03 | 5 MG
BTK degrader-1 is a Bruton's tyrosine kinase (BTK) bifunctional degrader that can be conjugated with CD79b. It has an anti-tumor effect.
- For research use only
- To be handled by experienced personnel in appropriately equipped and authorized facilities
- Not fully validated for medical applications
AdipoGen Guanidine thiocyanate
Chemical. CAS 593-84-0. Formula CH5N3 . CHNS. MW 59.07 . 59.09. Guanidine thiocyanate is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms and is commonly used in the guanidinium thiocyanate-phenol-chloroform extraction method. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine hydrochloride. It is useful for denaturation and refolding of proteins. At high molarity solutions, Guanidine thiocyanate irreversibly inactivates RNase. Guanidine thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.